Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1878PFAM: ABC-2 type transporter; KEGG: fra:Francci3_1473 hypothetical protein. (273 aa)    
Predicted Functional Partners:
Afer_1879
KEGG: ace:Acel_0339 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase.
  
 0.978
Afer_0729
PFAM: nitroreductase; KEGG: kra:Krad_1547 nitroreductase.
 
    0.679
Afer_0191
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tfu:Tfu_1989 ABC-type multidrug transport system ATPase componen.
  
 0.674
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
       0.648
Afer_1881
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: afl:Aflv_0505 isocitrate dehydrogenase.
       0.631
Afer_1206
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: aau:AAur_2052 putative antibiotic ABC transporter, ATP-binding protein.
  
 0.610
Afer_1044
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rrs:RoseRS_4617 ABC transporter related.
  
 0.583
Afer_1882
KEGG: ace:Acel_0470 hypothetical protein.
       0.541
Afer_0300
PFAM: ABC-2 type transporter; KEGG: mta:Moth_2298 daunorubicin resistance ABC transporter membrane protein.
  
  
 
0.537
Afer_0345
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sco:SCO2305 ABC transporter ATP-binding subunit.
 
  
 0.488
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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