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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)    
Predicted Functional Partners:
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.994
Afer_1835
KEGG: fre:Franean1_7227 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.994
Afer_1881
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: afl:Aflv_0505 isocitrate dehydrogenase.
  
 0.993
Afer_2022
KEGG: msm:MSMEG_4035 citrate synthase.
  
 0.992
Afer_1947
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; amino acid-binding ACT domain protein; malic protein domain protein; UBA/THIF- type NAD/FAD binding protein; KEGG: rxy:Rxyl_1110 malate dehydrogenase (oxaloacetate decarboxylating).
  
 0.975
Afer_0622
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; amino acid-binding ACT domain protein; malic protein domain protein; KEGG: nca:Noca_0113 malate dehydrogenase.
  
 0.961
Afer_1408
KEGG: bba:Bd2784 aconitate hydratase; TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein.
  
 0.940
Afer_0101
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.934
Afer_1732
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; KEGG: ace:Acel_0586 alpha-ketoglutarate decarboxylase.
 
 0.934
Afer_1531
PFAM: aminotransferase class I and II; KEGG: rsa:RSal33209_0984 aspartate aminotransferase.
  
 0.924
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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