STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1882KEGG: ace:Acel_0470 hypothetical protein. (392 aa)    
Predicted Functional Partners:
clpP
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.750
Afer_0855
PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: afe:Lferr_1745 hypothetical protein.
  
     0.701
Afer_1023
KEGG: afw:Anae109_1828 hypothetical protein.
  
     0.698
Afer_0577
KEGG: oih:OB1441 hypothetical protein.
  
     0.689
Afer_1562
PFAM: protein of unknown function DUF501; KEGG: rxy:Rxyl_0915 hypothetical protein.
  
   
 0.681
Afer_0682
KEGG: fra:Francci3_1402 hypothetical protein.
  
     0.680
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
    0.674
Afer_1881
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: afl:Aflv_0505 isocitrate dehydrogenase.
       0.658
Afer_1733
PFAM: alpha/beta hydrolase fold; KEGG: fre:Franean1_2175 alpha/beta hydrolase fold.
  
     0.641
Afer_1195
KEGG: scl:sce0507 hypothetical protein.
  
     0.608
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.