STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1886Actin-like ATPase involved in cell morphogenesis; KEGG: cbf:CLI_0218 mbl protein. (326 aa)    
Predicted Functional Partners:
Afer_0767
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.946
Afer_0541
KEGG: acr:Acry_1011 hypothetical protein.
   
 
 0.867
Afer_0769
Penicillin-binding protein 2; KEGG: fre:Franean1_5266 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain.
 
 
 
 0.819
Afer_0956
TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: nca:Noca_3461 rod shape-determining protein RodA; Belongs to the SEDS family.
 
 
 0.784
Afer_1884
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: mem:Memar_1334 molybdopterin biosynthesis MoaE.
       0.779
Afer_1885
Hypothetical protein.
       0.773
Afer_0089
PFAM: penicillin-binding protein transpeptidase; KEGG: ace:Acel_0020 peptidoglycan glycosyltransferase.
 
 
 
 0.592
Afer_1246
PFAM: cell cycle protein; KEGG: nfa:nfa17650 putative cell division protein; Belongs to the SEDS family.
 
 
 0.542
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
   0.528
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
    0.478
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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