STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1902PFAM: protein of unknown function DUF147; KEGG: stp:Strop_4270 DNA integrity scanning protein DisA; Belongs to the DisA family. (356 aa)    
Predicted Functional Partners:
ispF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
  
    0.871
Afer_1901
PFAM: transcription factor CarD; KEGG: mjl:Mjls_5126 CarD family transcriptional regulator.
 
     0.689
Afer_1899
TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: gur:Gura_2796 RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
    0.620
Afer_1903
PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: fal:FRAAL6680 ATP-dependent protease, HSP 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Belongs to the ClpA/ClpB family.
  
    0.600
Afer_1898
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pmy:Pmen_4599 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
       0.524
Afer_0028
TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: hau:Haur_0363 DegV family protein.
  
    0.485
Afer_1126
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: sma:SAV_6982 hypothetical protein.
  
     0.437
Afer_1897
PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: rha:RHA1_ro01635 permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family.
       0.423
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.