Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1928PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: nfa:nfa43360 hypothetical protein. (265 aa)    
Predicted Functional Partners:
Afer_1927
PFAM: protein of unknown function DUF6 transmembrane; KEGG: msm:MSMEG_2639 integral membrane protein.
       0.557
Afer_1929
Hypothetical protein; KEGG: aba:Acid345_0662 parallel beta-helix repeat protein.
       0.505
Afer_1994
KEGG: tfu:Tfu_0354 3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
 
      0.496
Afer_1182
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: mkm:Mkms_5833 4-oxalocrotonate decarboxylase.
  
  
 0.426
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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