Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_1931Transcriptional regulator of molybdate metabolism, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: scl:sce1136 putative regulator of molybdate uptake. (352 aa)    
Predicted Functional Partners:
Afer_1934
KEGG: bvi:Bcep1808_7294 tungstate/molybdate binding protein.
 
   
 0.919
Afer_1933
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bvi:Bcep1808_7295 tungstate/molybdate transport system permease protein.
 
   
 0.862
Afer_1932
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cms:CMS_2522 putative ABC transporter ATP- binding subunit.
       0.782
Afer_1930
KEGG: rrs:RoseRS_3572 hypothetical protein.
       0.608
Afer_1935
PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sgr:SGR_3424 putative aminotransferase.
       0.525
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.495
Afer_0274
Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor.
  
  
 0.481
Afer_1852
Hypothetical protein; KEGG: mmr:Mmar10_2710 molybdenum cofactor guanylyltransferase.
  
  
 0.409
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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