STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1977Hypothetical protein; KEGG: aba:Acid345_3948 NHL repeat protein. (655 aa)    
Predicted Functional Partners:
Afer_0648
PFAM: cell division FtsK/SpoIIIE; SMART: AAA ATPase; KEGG: ace:Acel_1501 cell division FtsK/SpoIIIE.
   
 
 0.756
Afer_1631
PFAM: protein of unknown function DUF255; KEGG: nfa:nfa48210 hypothetical protein.
    
   0.719
Afer_1507
PFAM: SMC domain protein; KEGG: sen:SACE_6071 chromosome segregation ATPase.
   
 
 0.558
Afer_0811
Endothelin-converting enzyme 1; PFAM: peptidase M13; peptidase M13 neprilysin; KEGG: lxx:Lxx01010 metallopeptidase.
  
    0.485
Afer_1978
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
       0.437
Afer_1979
KEGG: ace:Acel_2021 NAD/NADP transhydrogenase alpha subunit-like.
       0.437
Afer_1975
PFAM: glycosyl transferase group 1; KEGG: jan:Jann_4283 glycosyl transferase, group 1.
       0.413
Afer_1976
PFAM: glycosyl transferase group 1; KEGG: pap:PSPA7_6239 glycosyltransferase WbpX.
       0.413
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.