STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1981Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: regulatory protein LuxR; response regulator receiver; KEGG: cms:CMS_0994 putative two-component system response regulator. (222 aa)    
Predicted Functional Partners:
Afer_1982
Putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: kra:Krad_1351 integral membrane sensor signal transduction histidine kinase.
 
 
 0.966
Afer_0181
PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: mkm:Mkms_1071 GAF sensor signal transduction histidine kinase.
 
 
 0.873
Afer_0343
Putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: sco:SCO2307 two-component sensor kinase.
 
 
 0.808
Afer_0342
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: sco:SCO4072 LuxR family two component system response regulator.
  
     0.773
Afer_1980
PFAM: alanine dehydrogenase/PNT domain protein; KEGG: ade:Adeh_3005 alanine dehydrogenase/PNT-like protein.
       0.615
Afer_1983
PFAM: aminotransferase class-III; KEGG: nca:Noca_3921 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.553
Afer_1979
KEGG: ace:Acel_2021 NAD/NADP transhydrogenase alpha subunit-like.
     
 0.550
Afer_1978
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
       0.546
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.