STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1990PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: ace:Acel_1988 peptidase S1 and S6, chymotrypsin/Hap. (398 aa)    
Predicted Functional Partners:
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
 0.894
Afer_0559
PFAM: PDZ/DHR/GLGF domain protein; peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; KEGG: ace:Acel_1716 peptidase S1 and S6, chymotrypsin/Hap.
  
   
 0.758
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
     
 0.610
Afer_1753
PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: sth:STH1150 hypothetical protein.
   
  0.548
Afer_1994
KEGG: tfu:Tfu_0354 3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
  
  
 0.546
Afer_1993
PFAM: protein of unknown function DUF195; KEGG: psa:PST_2781 hypothetical protein.
       0.533
Afer_1991
PFAM: beta-lactamase domain protein; KEGG: tfu:Tfu_2040 Zn-dependent hydrolase.
       0.528
Afer_1992
Amidohydrolase; KEGG: nar:Saro_2348 peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerization domain protein.
       0.528
Afer_1825
PFAM: Cytochrome b/b6 domain; KEGG: fre:Franean1_1812 cytochrome b/b6 domain- containing protein.
 
  
 0.518
Afer_0380
KEGG: sen:SACE_2172 hypothetical protein.
  
   0.506
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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