Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1994KEGG: tfu:Tfu_0354 3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (286 aa)    
Predicted Functional Partners:
Afer_1996
SMART: Rhodanese domain protein; KEGG: mpa:MAP2046 SseB.
 
  
 
0.929
Afer_0500
Cysteine desulfurase; PFAM: aminotransferase class V; KEGG: ank:AnaeK_1104 aminotransferase class V.
   
 0.920
Afer_1531
PFAM: aminotransferase class I and II; KEGG: rsa:RSal33209_0984 aspartate aminotransferase.
     
  0.900
Afer_1495
PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: kra:Krad_1362 Cys/Met metabolism pyridoxal- phosphate-dependent protein.
  
 
 0.840
Afer_0269
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rxy:Rxyl_0463 pyridoxal-5'-phosphate- dependent enzyme, beta subunit.
  
 
 0.828
Afer_1336
TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: fal:FRAAL3350 subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.828
Afer_1991
PFAM: beta-lactamase domain protein; KEGG: tfu:Tfu_2040 Zn-dependent hydrolase.
   
 
 0.787
Afer_1992
Amidohydrolase; KEGG: nar:Saro_2348 peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerization domain protein.
       0.773
Afer_1993
PFAM: protein of unknown function DUF195; KEGG: psa:PST_2781 hypothetical protein.
       0.773
Afer_0728
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: mxa:MXAN_2588 molybdopterin biosynthesis protein MoeB.
  
 
 0.648
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.