Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1995TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: afe:Lferr_2531 ammonium transporter. (481 aa)    
Predicted Functional Partners:
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
 
  
 0.896
Afer_0697
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: bbr:BB0978 gamma-glutamyltranspeptidase precursor.
   
  
 0.645
Afer_0085
KEGG: rrs:RoseRS_2545 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
      
 0.619
Afer_1370
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: stp:Strop_1359 beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
      
 0.619
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.563
Afer_1385
KEGG: afe:Lferr_1405 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
      0.556
Afer_0243
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: fre:Franean1_1770 glutamine synthetase, type I.
  
  
 0.536
Afer_0242
PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase.
  
  
 0.534
Afer_1156
KEGG: afe:Lferr_2664 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; SMART: GGDEF domain containing protein; EAL domain protein.
 
      0.533
Afer_1081
PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; KEGG: fre:Franean1_2035 response regulator receiver/ANTAR domain-containing protein.
  
  
 0.508
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: medium (72%) [HD]