STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1997PFAM: ribonuclease BN; KEGG: ace:Acel_1654 ribonuclease BN. (350 aa)    
Predicted Functional Partners:
Afer_1772
PFAM: peptidase C60 sortase A and B; KEGG: kra:Krad_3106 peptidase C60 sortase A and B.
  
     0.682
Afer_0938
PFAM: cyclase/dehydrase; KEGG: fal:FRAAL0171 hypothetical protein.
  
     0.576
Afer_1742
TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; Two component regulator propeller; KEGG: ace:Acel_0423 SpoIID/LytB domain-containing protein.
 
     0.498
Afer_1897
PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: rha:RHA1_ro01635 permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family.
  
     0.480
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
       0.445
Afer_0157
Putative flagellar biosynthesis pathway protein; KEGG: nca:Noca_0741 flagellar biosynthetic protein FliR.
  
     0.440
Afer_0606
KEGG: fra:Francci3_2206 hypothetical protein.
  
     0.421
Afer_0237
PFAM: Anion-transporting ATPase; KEGG: rha:RHA1_ro04317 arsenate (2+)-transporting ATPase.
  
     0.405
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.