Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_2003PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: afu:AF0506 iron-sulfur binding reductase. (412 aa)    
Predicted Functional Partners:
Afer_0966
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: cts:Ctha_0136 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
  
 0.931
Afer_0965
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: cts:Ctha_0137 protein of unknown function DUF224 cysteine-rich region domain protein.
   
 0.917
Afer_0964
KEGG: cts:Ctha_0138 hypothetical protein.
    
 0.906
Afer_2002
PFAM: FAD linked oxidase domain protein; KEGG: pth:PTH_2230 FAD/FMN-containing dehydrogenases.
 
  
 0.897
Afer_2001
Hypothetical protein.
       0.775
Afer_2004
PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: msm:MSMEG_6700 regulatory protein.
     
 0.551
Afer_2005
KEGG: mva:Mvan_1847 hypothetical protein.
       0.543
Afer_1021
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Polysulphide reductase NrfD; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
  
 0.470
Afer_2000
PFAM: amino acid permease-associated region; KEGG: msm:MSMEG_6701 amino acid permease.
       0.449
Afer_0971
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: bph:Bphy_5959 hypothetical protein.
 
 
0.418
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.