STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_2004PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: msm:MSMEG_6700 regulatory protein. (245 aa)    
Predicted Functional Partners:
Afer_2005
KEGG: mva:Mvan_1847 hypothetical protein.
 
     0.939
Afer_0274
Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor.
 
  
 0.649
Afer_2002
PFAM: FAD linked oxidase domain protein; KEGG: pth:PTH_2230 FAD/FMN-containing dehydrogenases.
  
  
 0.557
Afer_2003
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: afu:AF0506 iron-sulfur binding reductase.
     
 0.551
Afer_2001
Hypothetical protein.
       0.543
Afer_1582
KEGG: fal:FRAAL3631 hypothetical protein.
  
     0.539
Afer_2000
PFAM: amino acid permease-associated region; KEGG: msm:MSMEG_6701 amino acid permease.
 
     0.457
Afer_0889
PFAM: FAD dependent oxidoreductase; KEGG: sgr:SGR_1833 putative FAD-dependent oxidoreductase.
  
     0.443
Afer_1614
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dsy:DSY4747 hypothetical protein.
  
  
 0.413
Afer_1409
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator.
  
  
 0.406
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.