STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_2005KEGG: mva:Mvan_1847 hypothetical protein. (220 aa)    
Predicted Functional Partners:
Afer_2004
PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: msm:MSMEG_6700 regulatory protein.
 
     0.939
Afer_0213
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: kra:Krad_0315 putative CheW protein.
  
 
 0.873
Afer_0212
CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: aba:Acid345_1524 CheA signal transduction histidine kinases.
  
 
 0.855
Afer_0889
PFAM: FAD dependent oxidoreductase; KEGG: sgr:SGR_1833 putative FAD-dependent oxidoreductase.
  
     0.629
Afer_2002
PFAM: FAD linked oxidase domain protein; KEGG: pth:PTH_2230 FAD/FMN-containing dehydrogenases.
   
   0.569
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
     
 0.545
Afer_2001
Hypothetical protein.
       0.543
Afer_2003
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: afu:AF0506 iron-sulfur binding reductase.
       0.543
Afer_2000
PFAM: amino acid permease-associated region; KEGG: msm:MSMEG_6701 amino acid permease.
 
     0.529
Afer_0273
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: nca:Noca_3382 agmatinase; Belongs to the arginase family.
  
     0.468
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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