Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_2023PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: krh:KRH_05070 L-carnitine dehydratase/bile acid-inducible protein F family protein; Belongs to the CoA-transferase III family. (394 aa)    
Predicted Functional Partners:
Afer_2022
KEGG: msm:MSMEG_4035 citrate synthase.
 
   0.831
Afer_1777
Citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; KEGG: sgr:SGR_1172 putative lyase; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.759
Afer_2020
Hypothetical protein.
       0.716
Afer_2021
PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: pas:Pars_0521 extradiol ring-cleavage dioxygenase III subunit B.
       0.714
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
      0.645
Afer_2024
PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: cgt:cgR_2273 hypothetical protein.
 
     0.603
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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