Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_2026KEGG: sma:SAV_6532 hypothetical protein. (155 aa)    
Predicted Functional Partners:
Afer_0094
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; KEGG: nfa:nfa21550 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
  
 0.698
Afer_2027
PFAM: major facilitator superfamily MFS_1; KEGG: ace:Acel_1673 EmrB/QacA family drug resistance transporter.
       0.658
Afer_0222
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: fre:Franean1_1037 3-hydroxybutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase.
  
 0.578
Afer_1375
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: ace:Acel_0147 3-hydroxyacyl-CoA dehydrogenase.
  
 0.578
Afer_1527
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: nca:Noca_4392 3-hydroxybutyryl-CoA dehydrogenase.
  
 0.578
Afer_0354
PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: ace:Acel_0685 electron transfer flavoprotein, alpha subunit.
  
 
 0.577
Afer_0970
PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: cts:Ctha_0131 electron transfer flavoprotein alpha subunit.
  
 
 0.577
Afer_0353
PFAM: Electron transfer flavoprotein alpha/beta- subunit; KEGG: sen:SACE_6197 electron transfer flavoprotein, beta subunit.
  
 
 0.565
Afer_0969
PFAM: Electron transfer flavoprotein alpha/beta- subunit; KEGG: cts:Ctha_0132 electron transfer flavoprotein alpha/beta-subunit.
  
 
 0.565
Afer_0085
KEGG: rrs:RoseRS_2545 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.555
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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