node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDZ82837.1 | SDZ94332.1 | SAMN05660964_00322 | SAMN05660964_00581 | precorrin-8X methylmutase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.799 |
SDZ82837.1 | SDZ95157.1 | SAMN05660964_00322 | SAMN05660964_00602 | precorrin-8X methylmutase. | Alpha-ribazole phosphatase. | 0.450 |
SDZ82837.1 | SDZ95226.1 | SAMN05660964_00322 | SAMN05660964_00604 | precorrin-8X methylmutase. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.876 |
SDZ82837.1 | SEB01969.1 | SAMN05660964_00322 | SAMN05660964_03169 | precorrin-8X methylmutase. | Alpha-ribazole phosphatase. | 0.462 |
SDZ82837.1 | cbiA | SAMN05660964_00322 | SAMN05660964_02339 | precorrin-8X methylmutase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.940 |
SDZ82837.1 | cobS | SAMN05660964_00322 | SAMN05660964_00584 | precorrin-8X methylmutase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.844 |
SDZ82837.1 | cobT | SAMN05660964_00322 | SAMN05660964_00603 | precorrin-8X methylmutase. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.851 |
SDZ82837.1 | cysG | SAMN05660964_00322 | SAMN05660964_00796 | precorrin-8X methylmutase. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.659 |
SDZ94332.1 | SDZ82837.1 | SAMN05660964_00581 | SAMN05660964_00322 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | precorrin-8X methylmutase. | 0.799 |
SDZ94332.1 | SDZ95157.1 | SAMN05660964_00581 | SAMN05660964_00602 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Alpha-ribazole phosphatase. | 0.489 |
SDZ94332.1 | SDZ95226.1 | SAMN05660964_00581 | SAMN05660964_00604 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.940 |
SDZ94332.1 | SEB01969.1 | SAMN05660964_00581 | SAMN05660964_03169 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Alpha-ribazole phosphatase. | 0.453 |
SDZ94332.1 | cbiA | SAMN05660964_00581 | SAMN05660964_02339 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.925 |
SDZ94332.1 | cobS | SAMN05660964_00581 | SAMN05660964_00584 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.877 |
SDZ94332.1 | cobT | SAMN05660964_00581 | SAMN05660964_00603 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.793 |
SDZ94332.1 | cysG | SAMN05660964_00581 | SAMN05660964_00796 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.625 |
SDZ95157.1 | SDZ82837.1 | SAMN05660964_00602 | SAMN05660964_00322 | Alpha-ribazole phosphatase. | precorrin-8X methylmutase. | 0.450 |
SDZ95157.1 | SDZ94332.1 | SAMN05660964_00602 | SAMN05660964_00581 | Alpha-ribazole phosphatase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.489 |
SDZ95157.1 | SDZ95226.1 | SAMN05660964_00602 | SAMN05660964_00604 | Alpha-ribazole phosphatase. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.971 |
SDZ95157.1 | cobS | SAMN05660964_00602 | SAMN05660964_00584 | Alpha-ribazole phosphatase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.875 |