STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA66986.1Nitroreductase. (207 aa)    
Predicted Functional Partners:
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.921
SEA34253.1
Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.883
SEB04012.1
Hypothetical protein.
  
 0.854
SEB04320.1
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family.
  
 0.854
SEA50320.1
Ribosomal protein S12 methylthiotransferase accessory factor.
  
  
 0.843
SEA69200.1
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
  
    0.838
SEA80275.1
Acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase.
   
 
 0.811
SEB12986.1
Long-chain acyl-CoA synthetase.
   
 
 0.773
SEB13118.1
Long-chain acyl-CoA synthetase.
   
 
 0.773
SEA39024.1
ABC-type multidrug transport system, permease component.
  
  
 0.751
Your Current Organism:
Thiothrix caldifontis
NCBI taxonomy Id: 525918
Other names: DSM 21228, T. caldifontis, Thiothrix caldifontis Chernousova et al. 2009, VKM B-2520, strain G1
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