STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA75169.1Xylose isomerase-like TIM barrel. (270 aa)    
Predicted Functional Partners:
SEA73327.1
UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase.
  
 
 0.955
SEA11253.1
Chorismate mutase.
     
 0.860
SEA73154.1
Hypothetical protein.
  
 
 0.661
SDZ92598.1
Sugar or nucleoside kinase, ribokinase family; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.618
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.618
SEA31120.1
Ketohexokinase.
  
 
 0.618
SEA86986.1
Fructokinase.
  
 
 0.618
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
    
 0.573
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 
 0.565
SEA24272.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.560
Your Current Organism:
Thiothrix caldifontis
NCBI taxonomy Id: 525918
Other names: DSM 21228, T. caldifontis, Thiothrix caldifontis Chernousova et al. 2009, VKM B-2520, strain G1
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