STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Apre_0048Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (189 aa)    
Predicted Functional Partners:
Apre_0047
TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bsu:BSU40100 alkyl hydroperoxide reductase (large subunit) and NADH dehydrogenase.
 
  
 0.992
Apre_0090
PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: har:HEAR0182 putative thioredoxin.
  
 0.978
Apre_0546
PFAM: Catalase domain protein; KEGG: ppd:Ppro_1932 catalase.
  
 
 0.814
Apre_0764
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; HI0933 family protein; KEGG: bha:BH3571 thioredoxin reductase (NADPH).
  
 
 0.794
Apre_1720
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; HI0933 family protein; KEGG: afw:Anae109_2361 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.794
Apre_1489
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_02447 pyridine nucleotide-disulphide oxidoreductase family protein.
  
 
 0.784
Apre_1721
PFAM: Thioredoxin domain; KEGG: bha:BH3098 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.703
Apre_1391
Ferritin Dps family protein; Iron-storage protein.
  
  
 0.678
Apre_0081
PFAM: acyl-CoA dehydrogenase domain protein; Rubredoxin-type Fe(Cys)4 protein; Electron transfer flavoprotein alpha subunit; Acyl-CoA dehydrogenase type 2 domain; KEGG: bcb:BCB4264_A5464 acyl-CoA dehydrogenase.
  
 
 0.657
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.636
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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