Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apre_0048Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (189 aa)    
Predicted Functional Partners:
Apre_0047
TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bsu:BSU40100 alkyl hydroperoxide reductase (large subunit) and NADH dehydrogenase.
 
  
 0.992
Apre_0090
PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: har:HEAR0182 putative thioredoxin.
  
 0.943
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.833
Apre_0764
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; HI0933 family protein; KEGG: bha:BH3571 thioredoxin reductase (NADPH).
  
 
 0.759
Apre_1720
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; HI0933 family protein; KEGG: afw:Anae109_2361 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.759
Apre_1143
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: bcr:BCAH187_A0593 transcriptional regulator, Fur family; Belongs to the Fur family.
  
  
 0.751
Apre_0282
PFAM: glutathione peroxidase; KEGG: gpx1; glutathione peroxidase Gpx1; K00432 glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.734
Apre_1489
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_02447 pyridine nucleotide-disulphide oxidoreductase family protein.
  
 
 0.734
Apre_1721
PFAM: Thioredoxin domain; KEGG: bha:BH3098 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.726
Apre_0546
PFAM: Catalase domain protein; KEGG: ppd:Ppro_1932 catalase.
  
 
 0.722
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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