Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apre_0090PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: har:HEAR0182 putative thioredoxin. (231 aa)    
Predicted Functional Partners:
Apre_0089
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_2976 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
    0.955
Apre_0048
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 0.943
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.932
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.865
Apre_0087
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pca:Pcar_3082 two component sensor histidine kinase.
 
 
 0.852
Apre_1086
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pca:Pcar_1844 NADP-reducing hydrogenase chain C.
  
 
 0.810
Apre_0088
Hypothetical protein.
       0.808
Apre_0086
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: amc:MADE_02297 response regulator in two- component regulatory system with PhoQ.
 
  
 0.800
Apre_0441
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 
 0.788
Apre_0559
PFAM: peptidase C1A papain; Ig domain protein group 2 domain protein; Rhodanese domain protein; SMART: peptidase C1A papain; Rhodanese domain protein; KEGG: sfu:Sfum_0222 peptidase C1A, papain.
   
 0.765
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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