Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apre_0098KEGG: bcb:BCB4264_A2483 L-serine dehydratase, iron- sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, alpha subunit; PFAM: serine dehydratase alpha chain. (291 aa)    
Predicted Functional Partners:
Apre_0097
KEGG: bcy:Bcer98_2835 L-serine dehydratase, iron- sulfur-dependent, beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, beta subunit; PFAM: serine dehydratase beta chain.
 
 0.999
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.962
Apre_1062
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cff:CFF8240_0743 threonine dehydratase.
  
 
 0.923
Apre_0954
KEGG: pca:Pcar_1862 serine O-acetyltransferase.
     
 0.912
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
     
 0.806
Apre_0364
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bph:Bphy_4478 glyoxalase/bleomycin resistance protein/dioxygenase.
    
  0.801
Apre_0096
PFAM: sodium:dicarboxylate symporter; KEGG: ilo:IL2299 Na+/H+-dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.567
Apre_1420
PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bce:BC3203 hypothetical protein.
  
    0.449
Apre_1042
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2957 pyruvate-flavodoxin oxidoreductase.
     
 0.441
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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