Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0126PFAM: ATP:guanido phosphotransferase; KEGG: bcy:Bcer98_0075 ATP:guanido phosphotransferase. (322 aa)    
Predicted Functional Partners:
Apre_0125
Uncharacterized protein with conserved CXXC pairs; KEGG: bha:BH0101 hypothetical protein.
 
 
 0.999
Apre_0124
Transcriptional repressor, CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes; KEGG: bar:GBAA0077 transcriptional regulator CtsR.
 
  
 0.975
Apre_0127
PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: bcy:Bcer98_0076 ATPase; Belongs to the ClpA/ClpB family.
 
 
 0.951
Apre_0030
PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: bcy:Bcer98_0885 ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.741
Apre_0351
PFAM: ATPase AAA-2 domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: wsu:WS0609 Clp protease ATP-binding subunit.
  
 
 0.741
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.741
Apre_0136
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
    0.672
Apre_0324
Hypothetical protein; KEGG: AGAP002737-PA.
  
     0.656
Apre_0408
KEGG: bca:BCE_3356 hypothetical protein.
  
     0.634
Apre_0163
KEGG: conserved hypothetical protein; K10401 kinesin family member 18/19.
  
     0.599
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
Server load: low (14%) [HD]