STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0135Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (432 aa)    
Predicted Functional Partners:
Apre_0316
KEGG: bcz:BCZK2240 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein.
     
  0.900
Apre_0888
Hypothetical protein; KEGG: hdu:HD1832 aminoacyl-histidine dipeptidase.
     
  0.900
Apre_0955
TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bcy:Bcer98_0063 cysteine synthase A.
    
  0.805
Apre_0188
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: nme:NMB1476 glutamate dehydrogenase, NAD- specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
  0.800
glsA
PFAM: Glutaminase, core; KEGG: Glutaminase family protein; K01425 glutaminase; Belongs to the glutaminase family.
     
  0.800
Apre_0442
PFAM: glutamine synthetase catalytic region; KEGG: sat:SYN_01613 glutamine synthetase.
     
  0.800
Apre_0550
TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_00606 glutamate synthase (NADPH).
     
  0.800
Apre_1624
PFAM: aminotransferase class I and II; KEGG: cco:CCC13826_0327 aminotransferase, class II.
    
  0.800
Apre_0136
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.781
Apre_0134
TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S- methyltransferase DNA binding; KEGG: prw:PsycPRwf_1002 methylated-DNA--protein- cysteine methyltransferase.
       0.581
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
Server load: low (30%) [HD]