STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0197PFAM: Peptidase M16C associated domain protein; peptidase M16 domain protein; KEGG: sfu:Sfum_1661 peptidase M16C associated domain protein. (949 aa)    
Predicted Functional Partners:
Apre_1045
PFAM: peptidase M24; creatinase; KEGG: xaa-pro aminopeptidase.
   
 
 0.674
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
  0.669
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.636
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
     
  0.621
Apre_0869
KEGG: bha:BH1086 required for glycogen biosynthesis.
     
  0.621
Apre_0196
KEGG: rlt:Rleg2_1581 hypothetical protein.
       0.552
Apre_0198
Hypothetical protein.
       0.550
Apre_0199
PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; KEGG: msu:MS1414 MviM protein.
       0.550
Apre_0195
PFAM: toxic anion resistance family protein; KEGG: bsu:BSU00260 hypothetical protein; Belongs to the TelA family.
       0.546
Apre_0194
KEGG: bsu:BSU15840 hypothetical protein.
       0.539
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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