| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Apre_0260 | Apre_0261 | Apre_0260 | Apre_0261 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: vsp:VS_1552 putative SAM dependant methyltransferase. | PFAM: GCN5-related N-acetyltransferase; KEGG: sbn:Sbal195_1671 GCN5-related N- acetyltransferase. | 0.840 |
| Apre_0260 | Apre_0262 | Apre_0260 | Apre_0262 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: vsp:VS_1552 putative SAM dependant methyltransferase. | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | 0.551 |
| Apre_0261 | Apre_0260 | Apre_0261 | Apre_0260 | PFAM: GCN5-related N-acetyltransferase; KEGG: sbn:Sbal195_1671 GCN5-related N- acetyltransferase. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: vsp:VS_1552 putative SAM dependant methyltransferase. | 0.840 |
| Apre_0261 | Apre_0262 | Apre_0261 | Apre_0262 | PFAM: GCN5-related N-acetyltransferase; KEGG: sbn:Sbal195_1671 GCN5-related N- acetyltransferase. | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | 0.551 |
| Apre_0262 | Apre_0260 | Apre_0262 | Apre_0260 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: vsp:VS_1552 putative SAM dependant methyltransferase. | 0.551 |
| Apre_0262 | Apre_0261 | Apre_0262 | Apre_0261 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | PFAM: GCN5-related N-acetyltransferase; KEGG: sbn:Sbal195_1671 GCN5-related N- acetyltransferase. | 0.551 |
| Apre_0262 | Apre_0782 | Apre_0262 | Apre_0782 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.908 |
| Apre_0262 | Apre_0784 | Apre_0262 | Apre_0784 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: gsu:GSU1756 dihydroorotate dehydrogenase, electron transfer subunit, putative. | 0.789 |
| Apre_0262 | gatA | Apre_0262 | Apre_0979 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.665 |
| Apre_0262 | purD | Apre_0262 | Apre_1107 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | KEGG: dno:DNO_1110 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; phosphoribosylamine/glycine ligase; PFAM: AIR synthase related protein domain protein; phosphoribosylglycinamide synthetase; protein of unknown function DUF201; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Belongs to the GARS family. | 0.846 |
| Apre_0262 | pyrB | Apre_0262 | Apre_0780 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | KEGG: vfm:VFMJ11_0396 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.914 |
| Apre_0262 | pyrD | Apre_0262 | Apre_0785 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.874 |
| Apre_0262 | pyrE | Apre_0262 | Apre_0786 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.895 |
| Apre_0262 | pyrF | Apre_0262 | Apre_0783 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: hne:HNE_0128 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.758 |
| Apre_0782 | Apre_0262 | Apre_0782 | Apre_0262 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypb:YPTS_2898 uracil-xanthine permease. | 0.908 |
| Apre_0782 | Apre_0784 | Apre_0782 | Apre_0784 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: gsu:GSU1756 dihydroorotate dehydrogenase, electron transfer subunit, putative. | 0.998 |
| Apre_0782 | purD | Apre_0782 | Apre_1107 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | KEGG: dno:DNO_1110 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; phosphoribosylamine/glycine ligase; PFAM: AIR synthase related protein domain protein; phosphoribosylglycinamide synthetase; protein of unknown function DUF201; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Belongs to the GARS family. | 0.586 |
| Apre_0782 | pyrB | Apre_0782 | Apre_0780 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | KEGG: vfm:VFMJ11_0396 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| Apre_0782 | pyrD | Apre_0782 | Apre_0785 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.999 |
| Apre_0782 | pyrE | Apre_0782 | Apre_0786 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.978 |