Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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[Homology]
Score
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (306 aa)    
Predicted Functional Partners:
Apre_0281
KEGG: dds:Ddes_1040 O-acetylhomoserine/O- acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase.
 
 
 0.993
Apre_1062
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cff:CFF8240_0743 threonine dehydratase.
   
 
 0.826
Apre_0097
KEGG: bcy:Bcer98_2835 L-serine dehydratase, iron- sulfur-dependent, beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, beta subunit; PFAM: serine dehydratase beta chain.
     
 0.806
Apre_0098
KEGG: bcb:BCB4264_A2483 L-serine dehydratase, iron- sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, alpha subunit; PFAM: serine dehydratase alpha chain.
     
 0.806
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.800
metN
ABC transporter related; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
  
    0.715
Apre_0275
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vvy:VV0891 ABC-type metal ion transport system, permease component.
  
    0.713
Apre_1221
KEGG: nha:Nham_2001 hypothetical protein.
  
    0.659
Apre_1254
KEGG: msu:MS0941 MetE protein.
 
  
 0.617
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.512
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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