STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0300PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: hypothetical protein; K01620 threonine aldolase. (337 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.936
Apre_1062
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cff:CFF8240_0743 threonine dehydratase.
 
 
 0.932
Apre_0302
PFAM: acyltransferase 3; KEGG: bsu:BSU27140 hypothetical protein.
  
    0.784
Apre_0301
KEGG: hypothetical protein.
     
 0.779
Apre_0299
KEGG: hypothetical protein.
       0.529
purD
KEGG: dno:DNO_1110 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; phosphoribosylamine/glycine ligase; PFAM: AIR synthase related protein domain protein; phosphoribosylglycinamide synthetase; protein of unknown function DUF201; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Belongs to the GARS family.
 
   
 0.463
Apre_0296
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bcy:Bcer98_2442 ABC transporter-related protein.
       0.427
Apre_0297
PFAM: inner-membrane translocator; KEGG: bcb:BCB4264_A3888 sugar ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.
       0.427
Apre_0298
PFAM: inner-membrane translocator; KEGG: bsu:BSU31570 hypothetical protein; Belongs to the binding-protein-dependent transport system permease family.
       0.427
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.