Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Apre_0354KEGG: bca:BCE_A0156 arsenite-translocating ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase. (580 aa)    
Predicted Functional Partners:
Apre_0355
PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; KEGG: cju:C8J_1458 arsenate reductase.
    
 0.960
Apre_0353
PFAM: Arsenical resistance operon trans-acting repressor ArsD; KEGG: rfr:Rfer_3665 arsenical resistance operon trans-acting repressor ArsD.
 
   
 0.954
Apre_0356
TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: nma:NMA2095 putative integral membrane efflux protein.
     
 0.848
pyrF
TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: hne:HNE_0128 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
 
 0.788
Apre_0352
Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: dvl:Dvul_0525 regulatory protein, ArsR.
 
   
 0.636
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
    
   0.628
Apre_0056
PFAM: Rhomboid family protein; KEGG: bsu:BSU24870 hypothetical protein.
   
   0.432
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
   0.412
Apre_1265
PFAM: FRG domain protein; KEGG: sfr:Sfri_2606 hypothetical protein.
    
   0.412
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.402
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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