STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0433PFAM: CMP/dCMP deaminase zinc-binding; KEGG: bha:BH1334 late competence operon required for DNA binding and uptake. (148 aa)    
Predicted Functional Partners:
Apre_0946
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
 0.943
tdk
PFAM: thymidine kinase; KEGG: hypothetical protein.
  
 
 0.932
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
 0.928
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
  0.908
cmk
KEGG: bha:BH1634 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
    
  0.903
Apre_0430
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bcy:Bcer98_1077 regulatory protein GntR HTH.
 
     0.801
Apre_0434
TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; sucrose-6F-phosphate phosphohydrolase; KEGG: vvy:VVA0262 hydrolase.
       0.782
Apre_0431
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bcb:BCB4264_A4187 ABC transporter, ATP- binding protein.
       0.772
Apre_0432
Hypothetical protein; KEGG: bcy:Bcer98_2778 acetoin transport permease protein.
       0.772
Apre_1045
PFAM: peptidase M24; creatinase; KEGG: xaa-pro aminopeptidase.
  
    0.573
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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