Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0519PFAM: protein of unknown function DUF328; KEGG: mmw:Mmwyl1_3597 hypothetical protein; Belongs to the UPF0246 family. (240 aa)    
Predicted Functional Partners:
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
       0.781
Apre_0521
PFAM: SMC domain protein; KEGG: bcb:BCB4264_A2326 putative exonuclease.
       0.781
Apre_0522
ATP-dependent nuclease subunit B-like protein; ATP-dependent DNA helicase.
       0.781
Apre_0523
UvrD/REP helicase; ATP-dependent DNA helicase.
       0.781
Apre_0517
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bce:BC4279 high-affinity zinc uptake system ATP-binding protein ZnuC.
  
    0.413
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
Server load: low (14%) [HD]