Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apre_0536PFAM: GCN5-related N-acetyltransferase; KEGG: bcr:BCAH187_A4903 acetyltransferase, GNAT family. (184 aa)    
Predicted Functional Partners:
Apre_0537
TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region.
 
    0.892
Apre_0538
PFAM: Chromosomal replication initiator DnaA; SMART: AAA ATPase; KEGG: bcr:BCAH187_A4023 putative prophage LambdaBa02, DNA replication protein DnaC.
 
    0.832
nnrE
Carbohydrate kinase, YjeF related protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.
  
    0.815
Apre_0535
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
    0.812
Apre_0533
Phosphoesterase RecJ domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
       0.808
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
       0.808
Apre_0532
KEGG: sat:SYN_00642 hypothetical protein.
       0.781
Apre_0892
KEGG: hypothetical protein.
  
     0.647
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
    0.631
Apre_1471
Putative signal transduction histidine kinase; KEGG: ppd:Ppro_2661 putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
     0.524
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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