Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apre_0544PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bcy:Bcer98_1043 acetoacetyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (242 aa)    
Predicted Functional Partners:
Apre_1351
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: mpo:Mpop_3667 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.821
Apre_0441
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 
 0.812
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.803
Apre_0546
PFAM: Catalase domain protein; KEGG: ppd:Ppro_1932 catalase.
  
 0.799
Apre_0081
PFAM: acyl-CoA dehydrogenase domain protein; Rubredoxin-type Fe(Cys)4 protein; Electron transfer flavoprotein alpha subunit; Acyl-CoA dehydrogenase type 2 domain; KEGG: bcb:BCB4264_A5464 acyl-CoA dehydrogenase.
  
 0.761
acpP
Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.728
Apre_1580
Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: dds:Ddes_1827 transcriptional regulator, Crp/Fnr family.
  
 0.726
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 
 0.724
Apre_0776
PFAM: metallophosphoesterase; KEGG: bcr:BCAH187_A1178 DNA repair exonuclease family protein.
   
 
 0.724
Apre_0545
PFAM: aldo/keto reductase; KEGG: ecf:ECH74115_4323 2,5-didehydrogluconate reductase A.
  
 
 0.701
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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