Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0550TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_00606 glutamate synthase (NADPH). (463 aa)    
Predicted Functional Partners:
Apre_0551
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sat:SYN_00607 ferredoxin--NADP(+) reductase subunit alpha.
 
 
 0.998
Apre_1086
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pca:Pcar_1844 NADP-reducing hydrogenase chain C.
 
 
 0.985
Apre_0188
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: nme:NMB1476 glutamate dehydrogenase, NAD- specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.936
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.919
glsA
PFAM: Glutaminase, core; KEGG: Glutaminase family protein; K01425 glutaminase; Belongs to the glutaminase family.
     
 0.911
Apre_0442
PFAM: glutamine synthetase catalytic region; KEGG: sat:SYN_01613 glutamine synthetase.
    
 0.911
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.906
Apre_1100
PFAM: Citrate synthase; KEGG: bca:BCE_4725 methylcitrate synthase.
   
 
 0.829
Apre_0503
PFAM: Aldehyde Dehydrogenase; KEGG: bce:BC1285 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.825
Apre_1153
PFAM: Aldehyde Dehydrogenase; KEGG: pca:Pcar_1701 aldehyde dehydrogenase, NAD- linked; Belongs to the aldehyde dehydrogenase family.
   
 0.825
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
Server load: low (20%) [HD]