| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Apre_0039 | Apre_1112 | Apre_0039 | Apre_1112 | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: bar:GBAA1894 pyrimidine-nucleoside phosphorylase. | PFAM: Amidohydrolase 3; amidohydrolase; KEGG: net:Neut_1722 N-isopropylammelide isopropylaminohydrolase. | 0.911 |
| Apre_0039 | Apre_1281 | Apre_0039 | Apre_1281 | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: bar:GBAA1894 pyrimidine-nucleoside phosphorylase. | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: bha:BH1275 uridine kinase. | 0.933 |
| Apre_0039 | upp | Apre_0039 | Apre_0756 | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: bar:GBAA1894 pyrimidine-nucleoside phosphorylase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.924 |
| Apre_0755 | glyA | Apre_0755 | Apre_0915 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.795 |
| Apre_0755 | murA | Apre_0755 | Apre_0757 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.787 |
| Apre_0755 | prmC | Apre_0755 | Apre_0752 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.960 |
| Apre_0755 | upp | Apre_0755 | Apre_0756 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.804 |
| Apre_1071 | Apre_1281 | Apre_1071 | Apre_1281 | PFAM: Maf family protein; KEGG: bsu:BSU28050 Maf-like protein; Belongs to the Maf family. | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: bha:BH1275 uridine kinase. | 0.903 |
| Apre_1071 | pyrF | Apre_1071 | Apre_0783 | PFAM: Maf family protein; KEGG: bsu:BSU28050 Maf-like protein; Belongs to the Maf family. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: hne:HNE_0128 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.900 |
| Apre_1071 | pyrH | Apre_1071 | Apre_0646 | PFAM: Maf family protein; KEGG: bsu:BSU28050 Maf-like protein; Belongs to the Maf family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| Apre_1071 | upp | Apre_1071 | Apre_0756 | PFAM: Maf family protein; KEGG: bsu:BSU28050 Maf-like protein; Belongs to the Maf family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
| Apre_1112 | Apre_0039 | Apre_1112 | Apre_0039 | PFAM: Amidohydrolase 3; amidohydrolase; KEGG: net:Neut_1722 N-isopropylammelide isopropylaminohydrolase. | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: bar:GBAA1894 pyrimidine-nucleoside phosphorylase. | 0.911 |
| Apre_1112 | upp | Apre_1112 | Apre_0756 | PFAM: Amidohydrolase 3; amidohydrolase; KEGG: net:Neut_1722 N-isopropylammelide isopropylaminohydrolase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.928 |
| Apre_1281 | Apre_0039 | Apre_1281 | Apre_0039 | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: bha:BH1275 uridine kinase. | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: bar:GBAA1894 pyrimidine-nucleoside phosphorylase. | 0.933 |
| Apre_1281 | Apre_1071 | Apre_1281 | Apre_1071 | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: bha:BH1275 uridine kinase. | PFAM: Maf family protein; KEGG: bsu:BSU28050 Maf-like protein; Belongs to the Maf family. | 0.903 |
| Apre_1281 | pyrF | Apre_1281 | Apre_0783 | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: bha:BH1275 uridine kinase. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: hne:HNE_0128 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.913 |
| Apre_1281 | pyrH | Apre_1281 | Apre_0646 | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: bha:BH1275 uridine kinase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.924 |
| Apre_1281 | upp | Apre_1281 | Apre_0756 | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: bha:BH1275 uridine kinase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.998 |
| glyA | Apre_0755 | Apre_0915 | Apre_0755 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.795 |
| glyA | upp | Apre_0915 | Apre_0756 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.796 |