Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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recD2Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (719 aa)    
Predicted Functional Partners:
Apre_0523
UvrD/REP helicase; ATP-dependent DNA helicase.
  
 
 0.862
Apre_1413
KEGG: bce:BC2815 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP- dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; HRDC domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein.
  
 
 0.831
Apre_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.827
Apre_0755
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
 
   0.811
Apre_0759
KEGG: ott:OTT_1626 hypothetical protein.
       0.809
murA
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.790
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.759
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.758
Apre_0754
TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: msu:MS1293 MMT1 protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
    0.734
Apre_0521
PFAM: SMC domain protein; KEGG: bcb:BCB4264_A2326 putative exonuclease.
   
 
 0.729
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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