Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0773PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bbt:BBta_3436 putative ABC transporter, ATP- binding protein. (233 aa)    
Predicted Functional Partners:
Apre_0774
PFAM: protein of unknown function DUF214; KEGG: lpc:LPC_0234 hypothetical protein.
 
 
 0.998
Apre_0687
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bra:BRADO0891 peptide ABC transporter ATP- binding protein.
 
    
0.718
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.639
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
       0.635
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.629
Apre_0289
PFAM: protein of unknown function DUF214; KEGG: bha:BH3121 hypothetical protein.
 
 0.618
Apre_0775
PFAM: Phosphoglycerate mutase; KEGG: pfkfb2; 6-phosphofructo-2-kinase/fructose-2,6- biphosphatase 2.
       0.584
Apre_0776
PFAM: metallophosphoesterase; KEGG: bcr:BCAH187_A1178 DNA repair exonuclease family protein.
       0.584
Apre_0777
KEGG: hypothetical protein.
       0.584
Apre_0778
PFAM: metallophosphoesterase; KEGG: mxa:MXAN_0344 metallophosphoesterase.
  
    0.584
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.