STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0774PFAM: protein of unknown function DUF214; KEGG: lpc:LPC_0234 hypothetical protein. (1143 aa)    
Predicted Functional Partners:
Apre_0773
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bbt:BBta_3436 putative ABC transporter, ATP- binding protein.
 
 
 0.998
Apre_0478
PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: pla:Plav_1100 ABC transporter related.
 
 
 0.989
Apre_0743
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: aba:Acid345_2827 ABC transporter, ATPase subunit.
 
 
 0.971
Apre_0287
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vpa:VP1995 ABC transporter, ATP-binding protein.
  
 
 0.965
Apre_1091
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bcb:BCB4264_A4956 efflux ABC transporter, ATP- binding protein.
  
 
 0.965
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
   0.756
Apre_1025
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.718
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.712
Apre_0776
PFAM: metallophosphoesterase; KEGG: bcr:BCAH187_A1178 DNA repair exonuclease family protein.
  
   0.677
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.677
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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