STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apre_0776PFAM: metallophosphoesterase; KEGG: bcr:BCAH187_A1178 DNA repair exonuclease family protein. (337 aa)    
Predicted Functional Partners:
Apre_0521
PFAM: SMC domain protein; KEGG: bcb:BCB4264_A2326 putative exonuclease.
  
 0.989
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.977
Apre_0777
KEGG: hypothetical protein.
 
 
 0.964
Apre_1413
KEGG: bce:BC2815 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP- dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; HRDC domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein.
  
 0.921
Apre_0779
PFAM: adenylate cyclase.
 
     0.828
Apre_0778
PFAM: metallophosphoesterase; KEGG: mxa:MXAN_0344 metallophosphoesterase.
       0.805
Apre_0544
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bcy:Bcer98_1043 acetoacetyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.798
Apre_0995
PFAM: DEAD_2 domain protein; SMART: helicase c2; Helicase-like, DEXD box c2 type; KEGG: bph:Bphy_5309 DEAD_2 domain-containing protein.
   
 0.787
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.787
Apre_0775
PFAM: Phosphoglycerate mutase; KEGG: pfkfb2; 6-phosphofructo-2-kinase/fructose-2,6- biphosphatase 2.
       0.782
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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