Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apre_0893Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (318 aa)    
Predicted Functional Partners:
Apre_0892
KEGG: hypothetical protein.
 
     0.877
Apre_0891
KEGG: hypothetical protein.
 
     0.836
Apre_0897
KEGG: hypothetical protein.
 
     0.836
Apre_0895
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: ban:BA1975 DNA-binding response regulator.
       0.808
Apre_0894
PFAM: ROK family protein; KEGG: bha:BH1425 glucose kinase.
       0.789
Apre_0896
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: ban:BA1976 sensor histidine kinase.
  
    0.789
Apre_0888
Hypothetical protein; KEGG: hdu:HD1832 aminoacyl-histidine dipeptidase.
 
     0.704
Apre_0890
KEGG: dal:Dalk_2634 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
    0.680
Apre_0887
PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: gme:Gmet_3548 PpiC-type peptidyl-prolyl cis- trans isomerase.
   
   0.675
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.667
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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