Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Apre_1100PFAM: Citrate synthase; KEGG: bca:BCE_4725 methylcitrate synthase. (450 aa)    
Predicted Functional Partners:
Apre_1102
TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: dvl:Dvul_1930 aconitate hydratase.
 
 0.997
Apre_1101
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sse:Ssed_3318 isocitrate dehydrogenase.
 
 0.989
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.984
Apre_1351
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: mpo:Mpop_3667 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.975
Apre_1042
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2957 pyruvate-flavodoxin oxidoreductase.
  
 0.965
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.963
ldh-2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.963
Apre_1063
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_4144 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.954
Apre_0229
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: bcb:BCB4264_A4713 putative malate dehydrogenase.
  
 
 0.944
Apre_1356
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: bcb:BCB4264_A5464 acyl-CoA dehydrogenase.
  
 0.942
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.