STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apre_1101PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sse:Ssed_3318 isocitrate dehydrogenase. (344 aa)    
Predicted Functional Partners:
Apre_1102
TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: dvl:Dvul_1930 aconitate hydratase.
 0.995
Apre_1100
PFAM: Citrate synthase; KEGG: bca:BCE_4725 methylcitrate synthase.
 
 0.953
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: bcb:BCB4264_A4737 argininosuccinate lyase.
  
 
 0.867
Apre_0188
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: nme:NMB1476 glutamate dehydrogenase, NAD- specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.849
Apre_0550
TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_00606 glutamate synthase (NADPH).
  
 
 0.819
Apre_0092
PFAM: fumarate lyase; KEGG: bha:BH1426 aspartate ammonia-lyase.
    
  0.800
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.783
Apre_1086
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pca:Pcar_1844 NADP-reducing hydrogenase chain C.
  
 
 0.762
purD
KEGG: dno:DNO_1110 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; phosphoribosylamine/glycine ligase; PFAM: AIR synthase related protein domain protein; phosphoribosylglycinamide synthetase; protein of unknown function DUF201; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Belongs to the GARS family.
  
 
 0.707
purC
PFAM: SAICAR synthetase; KEGG: sat:SYN_00107 phosphoribosylaminoimidazole- succinocarboxamide synthase.
  
  
 0.624
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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