Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apre_1102TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: dvl:Dvul_1930 aconitate hydratase. (642 aa)    
Predicted Functional Partners:
Apre_1100
PFAM: Citrate synthase; KEGG: bca:BCE_4725 methylcitrate synthase.
 
 0.997
Apre_1101
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sse:Ssed_3318 isocitrate dehydrogenase.
 
 0.987
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.957
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.893
ldh-2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.893
Apre_1099
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bcb:BCB4264_A2322 enoyl-CoA hydratase/isomerase family protein.
  
 0.860
rpmF
TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: ppd:Ppro_1740 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
 0.830
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.827
Apre_1086
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pca:Pcar_1844 NADP-reducing hydrogenase chain C.
  
 
 0.825
Apre_1351
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: mpo:Mpop_3667 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.805
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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