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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa)    
Predicted Functional Partners:
Apre_1700
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.952
Apre_0946
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
 
 0.945
tdk
PFAM: thymidine kinase; KEGG: hypothetical protein.
  
 
 0.937
Apre_1696
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
 
 0.928
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.926
Apre_0433
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: bha:BH1334 late competence operon required for DNA binding and uptake.
    
 0.918
Apre_1071
PFAM: Maf family protein; KEGG: bsu:BSU28050 Maf-like protein; Belongs to the Maf family.
  
 
  0.909
Apre_1127
PFAM: protein of unknown function DUF970; KEGG: bha:BH0043 hypothetical protein.
 
    0.845
Apre_1126
KEGG: pca:Pcar_1692 DNA polymerase III, gamma/tau subunits.
  
  
 0.838
Apre_1125
PFAM: PSP1 domain protein; KEGG: bsu:BSU00320 hypothetical protein.
  
    0.818
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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