Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Apre_1143Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: bcr:BCAH187_A0593 transcriptional regulator, Fur family; Belongs to the Fur family. (150 aa)    
Predicted Functional Partners:
Apre_0048
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.751
Apre_0515
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: aeh:Mlg_0939 ferric uptake regulator family protein; Belongs to the Fur family.
  
     0.712
Apre_0940
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: cff:CFF8240_1143 ferric uptake regulation protein; Belongs to the Fur family.
  
     0.693
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.611
Apre_1657
PFAM: Rubrerythrin; KEGG: sat:SYN_02523 rubrerythrin.
 
  
 0.569
rplL
Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
  
    0.543
rplJ
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
    0.482
Apre_1721
PFAM: Thioredoxin domain; KEGG: bha:BH3098 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.454
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.444
Apre_0705
Iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; SMART: iron dependent repressor; KEGG: tcx:Tcr_0904 iron dependent repressor.
  
  
 0.423
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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