Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apre_1181PFAM: Uracil-DNA glycosylase superfamily; KEGG: hip:CGSHiEE_02100 hypothetical protein. (190 aa)    
Predicted Functional Partners:
Apre_0183
PFAM: peptidase M22 glycoprotease; KEGG: bha:BH0546 glycoprotein endopeptidase.
  
    0.662
Apre_1179
KEGG: msu:MS1725 hypothetical protein.
  
  
 0.656
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
    0.623
Apre_1180
Hypothetical protein; KEGG: net:Neut_0709 oxidoreductase FAD/NAD(P)- binding subunit.
       0.601
Apre_1183
TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: bcb:BCB4264_A3937 signal peptidase I S; Belongs to the peptidase S26 family.
       0.576
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.562
Apre_1178
PFAM: GCN5-related N-acetyltransferase; KEGG: pmr:PMI1249 acetyltransferase.
  
    0.528
Apre_1177
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
    0.526
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.433
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
       0.401
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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