Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Apre_1216Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: swd:Swoo_3963 integral membrane sensor signal transduction histidine kinase. (441 aa)    
Predicted Functional Partners:
Apre_1215
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bha:BH0820 two-component response regulator.
 
 
 0.976
Apre_0895
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: ban:BA1975 DNA-binding response regulator.
 
 0.888
Apre_0086
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: amc:MADE_02297 response regulator in two- component regulatory system with PhoQ.
 
 
 0.872
Apre_1374
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcr:BCAH187_A1453 DNA-binding response regulator.
 
 
 0.871
Apre_0643
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bha:BH3426 two-component response regulator.
 
 
 0.780
Apre_1093
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bha:BH3911 two-component response regulator.
 
 
 0.760
Apre_1217
PFAM: peptidase S41; KEGG: hypothetical protein.
       0.754
Apre_0741
Two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; response regulator receiver; SMART: response regulator receiver; KEGG: gbm:Gbem_0243 two component transcriptional regulator, winged helix family.
 
 
 0.747
Apre_0478
PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: pla:Plav_1100 ABC transporter related.
  
 
 0.715
Apre_1618
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: bsu:BSU35960 ribose ABC transporter (ribose- binding protein).
    
 
 0.709
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.