STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apre_1253TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: bca:BCE_4345 5-formyltetrahydrofolate cyclo- ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (177 aa)    
Predicted Functional Partners:
Apre_1131
PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: bha:BH2784 methylenetetrahydrofolate dehydrogenase.
    
 0.930
purN
Formyl transferase domain protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.928
Apre_1252
TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN; KEGG: bcb:BCB4264_A0474 YihY family protein; Belongs to the UPF0761 family.
       0.783
Apre_1251
PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: bsu:BSU32230 hypothetical protein.
       0.782
Apre_0056
PFAM: Rhomboid family protein; KEGG: bsu:BSU24870 hypothetical protein.
  
    0.652
Apre_1250
TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: bha:BH3608 ribosomal protein S30AE familyprotein.
  
    0.542
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.504
purD
KEGG: dno:DNO_1110 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; phosphoribosylamine/glycine ligase; PFAM: AIR synthase related protein domain protein; phosphoribosylglycinamide synthetase; protein of unknown function DUF201; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Belongs to the GARS family.
 
    0.446
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
   
 0.438
pheT
KEGG: bha:BH3110 phenylalanyl-tRNA synthetase subunit beta; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
  
  
 0.435
Your Current Organism:
Anaerococcus prevotii DSM 20548
NCBI taxonomy Id: 525919
Other names: A. prevotii DSM 20548, Anaerococcus prevotii ATCC 9321, Anaerococcus prevotii CCUG 41932, Anaerococcus prevotii str. DSM 20548, Anaerococcus prevotii strain DSM 20548
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